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Bu madde, ; zira herhangi bir maddeden bu maddeye verilmiş bir bağlantı yoktur. (Şubat 2024) |
Aldehit dehidrogenaz aile 3, üye A1, insanların 17. kromozomunda yer alan ALDH3A1 geni tarafından kodlanan bir enzimdir.
| ALDH3A1 | |||||||||||||||||||||||||
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| Tanımlayıcılar | |||||||||||||||||||||||||
| ALDH3A1 | |||||||||||||||||||||||||
| Dış kimlikler | OMIM: 100660 1353451 20175 ALDH3A1 | ||||||||||||||||||||||||
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| Türler | İnsan | Fare | |||||||||||||||||||||||
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| RefSeq (mRNA) |
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| RefSeq (protein) |
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| Yerleşim (UCSC) | Krom. 17: 19.74 – 19.75 Mb | n/a | |||||||||||||||||||||||
| PubMed araması | |||||||||||||||||||||||||
| Vikiveri | |||||||||||||||||||||||||
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Kaynakça
- ^ a b c GRCh38: Ensembl release 89: ENSG00000108602 - , May 2017
- ^ "İnsan PubMed Başvurusu:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Fare PubMed Başvurusu:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ Hiraoka LR, Hsu L, Hsieh CL (Jul 1995). "Assignment of ALDH3 to human chromosome 17p11.2 and ALDH5 to human chromosome 9p13". Genomics. 25 (1). ss. 323-5. doi:10.1016/0888-7543(95)80150-K. (PMID) 7774944.
- ^ Hsu LC, Chang WC, Shibuya A, Yoshida A (Mar 1992). "Human stomach aldehyde dehydrogenase cDNA and genomic cloning, primary structure, and expression in Escherichia coli". J Biol Chem. 267 (5). ss. 3030-7. doi:10.1016/S0021-9258(19)50690-1. (PMID) 1737758.
- ^ "Entrez Gene: ALDH3A1 aldehyde dehydrogenase 3 family, memberA1". 11 Mayıs 2009 tarihinde kaynağından arşivlendi. Erişim tarihi: 11 Şubat 2024.
Ek okuma
- Yoshida A (1993). "Molecular genetics of human aldehyde dehydrogenase". Pharmacogenetics. 2 (4). ss. 139-47. doi:10.1097/00008571-199208000-00001. (PMID) 1306115.
- Vasiliou V, Bairoch A, Tipton KF, Nebert DW (2000). "Eukaryotic aldehyde dehydrogenase (ALDH) genes: human polymorphisms, and recommended nomenclature based on divergent evolution and chromosomal mapping". Pharmacogenetics. 9 (4). ss. 421-34. (PMID) 10780262.
- Eckey R, Timmann R, Hempel J, ve diğerleri. (1991). "Biochemical, Immunological, and Molecular Characterization of a "High KM" Aldehyde Dehydrogenase". Enzymology and Molecular Biology of Carbonyl Metabolism 3. Advances in Experimental Medicine and Biology. 284. ss. 43-52. doi:10.1007/978-1-4684-5901-2_6. ISBN . (PMID) 1905102.
- Yin SJ, Vagelopoulos N, Wang SL, Jörnvall H (1991). "Structural features of stomach aldehyde dehydrogenase distinguish dimeric aldehyde dehydrogenase as a 'variable' enzyme. 'Variable' and 'constant' enzymes within the alcohol and aldehyde dehydrogenase families". FEBS Lett. 283 (1). ss. 85-8. doi:10.1016/0014-5793(91)80559-L. (PMID) 2037078.
- Santisteban I, Povey S, West LF, ve diğerleri. (1986). "Chromosome assignment, biochemical and immunological studies on a human aldehyde dehydrogenase, ALDH3". Ann. Hum. Genet. 49 (Pt 2). ss. 87-100. doi:10.1111/j.1469-1809.1985.tb01680.x. (PMID) 4073832.
- Teng YS (1981). "Stomach aldehyde dehydrogenase: report of a new locus". Hum. Hered. 31 (2). ss. 74-7. doi:10.1159/000153181. (PMID) 7228061.
- Dyck LE (1995). "Polymorphism of a class 3 aldehyde dehydrogenase present in human saliva and in hair roots". Alcohol. Clin. Exp. Res. 19 (2). ss. 420-6. doi:10.1111/j.1530-0277.1995.tb01525.x. (PMID) 7625577.
- Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2). ss. 171-4. doi:10.1016/0378-1119(94)90802-8. (PMID) 8125298.
- Hsu LC, Yoshida A (1993). "Human Stomach Aldehyde Dehydrogenase, ALDH3". Enzymology and Molecular Biology of Carbonyl Metabolism 4. Advances in Experimental Medicine and Biology. 328. ss. 141-52. doi:10.1007/978-1-4615-2904-0_16. ISBN . (PMID) 8493892.
- Rogers GR, Markova NG, De Laurenzi V, ve diğerleri. (1997). "Genomic organization and expression of the human fatty aldehyde dehydrogenase gene (FALDH)". Genomics. 39 (2). ss. 127-35. doi:10.1006/geno.1996.4501. (PMID) 9027499.
- Tsukamoto N, Chang C, Yoshida A (1997). "Mutations associated with Sjögren-Larsson syndrome". Ann. Hum. Genet. 61 (Pt 3). ss. 235-42. doi:10.1046/j.1469-1809.1997.6130235.x. (PMID) 9250352.
- Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, ve diğerleri. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2). ss. 149-56. doi:10.1016/S0378-1119(97)00411-3. (PMID) 9373149.
- Rekha GK, Devaraj VR, Sreerama L, ve diğerleri. (1998). "Inhibition of human class 3 aldehyde dehydrogenase, and sensitization of tumor cells that express significant amounts of this enzyme to oxazaphosphorines, by chlorpropamide analogues". Biochem. Pharmacol. 55 (4). ss. 465-74. doi:10.1016/S0006-2952(97)00475-9. (PMID) 9514081.
- Simpson JC, Wellenreuther R, Poustka A, ve diğerleri. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. 1 (3). ss. 287-92. doi:10.1093/embo-reports/kvd058. (PMC) 1083732 $2. (PMID) 11256614.
- Rodriguez-Zavala JS, Weiner H (2002). "Structural aspects of aldehyde dehydrogenase that influence dimer-tetramer formation". Biochemistry. 41 (26). ss. 8229-37. doi:10.1021/bi012081x. (PMID) 12081471.
- Yang M, Coles BF, Delongchamp R, ve diğerleri. (2003). "Effects of the ADH3, CYP2E1, and GSTP1 genetic polymorphisms on their expressions in Caucasian lung tissue". Lung Cancer. 38 (1). ss. 15-21. doi:10.1016/S0169-5002(02)00150-2. (PMID) 12367788.
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Bu madde oksuz maddedir zira herhangi bir maddeden bu maddeye verilmis bir baglanti yoktur Lutfen ilgili maddelerden bu sayfaya baglanti vermeye calisin Subat 2024 Aldehit dehidrogenaz aile 3 uye A1 insanlarin 17 kromozomunda yer alan ALDH3A1 geni tarafindan kodlanan bir enzimdir ALDH3A1Uygun yapilarPDBOrtolog aramasi PDBe RCSBPDB kimlik kodlarinin listesi3SZA 3SZB 4H80 4L1O 4L2OTanimlayicilarALDH3A1Dis kimliklerOMIM 100660 1353451 20175 ALDH3A1Gen yerlesimi Insan Krom Bant17p11 2Baslangic19 737 984 bcBitis19 748 943 bcRNA ekspresyonu deseniDaha cok ekspresyon verisi basvurusuGen ontolojisiMolekuler islevi benzaldehyde dehydrogenase NAD activity oxidoreductase activity acting on the aldehyde or oxo group of donors NAD or NADP as acceptor GO 0001948 GO 0016582 protein baglanmasi oxidoreductase activity aldehyde dehydrogenase NAD activity alcohol dehydrogenase NADP activity aldehyde dehydrogenase NAD P activity 3 chloroallyl aldehyde dehydrogenase activityHucresel bileseni integral component of membrane Hucre zari Endoplazmik retikulum extracellular space sitoplazma Sitozol Nukleoplazma intracellular membrane bounded organelleBiyolojik sureci response to hypoxia GO 1904578 response to organic cyclic compound response to nutrient GO 0010260 hucre yaslanmasi response to glucocorticoid cellular aldehyde metabolic process positive regulation of cell population proliferation xenobiotic metabolic process Metabolizma response to cAMPKaynaklar Amigo QuickGOTurlerInsanFare21811670ENSG00000108602ENSMUSG00000019102P30838P47739RefSeq mRNA NM 000691 NM 001135167 NM 001135168 NM 001330150NM 001112725 NM 007436 NM 001331112RefSeq protein NP 000682 NP 001128639 NP 001128640 NP 001317079NP 001106196 NP 001318041 NP 031462Yerlesim UCSC Krom 17 19 74 19 75 Mbn aPubMed aramasiVikiveriInsan i Gor DuzenleFare yi Gor DuzenleKaynakca a b c GRCh38 Ensembl release 89 ENSG00000108602 May 2017 Insan PubMed Basvurusu National Center for Biotechnology Information U S National Library of Medicine Arsivlenmesi gereken baglantiya sahip kaynak sablonu iceren maddeler link Fare PubMed Basvurusu National Center for Biotechnology Information U S National Library of Medicine Arsivlenmesi gereken baglantiya sahip kaynak sablonu iceren maddeler link Hiraoka LR Hsu L Hsieh CL Jul 1995 Assignment of ALDH3 to human chromosome 17p11 2 and ALDH5 to human chromosome 9p13 Genomics 25 1 ss 323 5 doi 10 1016 0888 7543 95 80150 K PMID 7774944 Hsu LC Chang WC Shibuya A Yoshida A Mar 1992 Human stomach aldehyde dehydrogenase cDNA and genomic cloning primary structure and expression in Escherichia coli J Biol Chem 267 5 ss 3030 7 doi 10 1016 S0021 9258 19 50690 1 PMID 1737758 Entrez Gene ALDH3A1 aldehyde dehydrogenase 3 family memberA1 11 Mayis 2009 tarihinde kaynagindan arsivlendi Erisim tarihi 11 Subat 2024 Ek okumaYoshida A 1993 Molecular genetics of human aldehyde dehydrogenase Pharmacogenetics 2 4 ss 139 47 doi 10 1097 00008571 199208000 00001 PMID 1306115 Vasiliou V Bairoch A Tipton KF Nebert DW 2000 Eukaryotic aldehyde dehydrogenase ALDH genes human polymorphisms and recommended nomenclature based on divergent evolution and chromosomal mapping Pharmacogenetics 9 4 ss 421 34 PMID 10780262 Eckey R Timmann R Hempel J ve digerleri 1991 Biochemical Immunological and Molecular Characterization of a High KM Aldehyde Dehydrogenase Enzymology and Molecular Biology of Carbonyl Metabolism 3 Advances in Experimental Medicine and Biology 284 ss 43 52 doi 10 1007 978 1 4684 5901 2 6 ISBN 978 1 4684 5903 6 PMID 1905102 Yin SJ Vagelopoulos N Wang SL Jornvall H 1991 Structural features of stomach aldehyde dehydrogenase distinguish dimeric aldehyde dehydrogenase as a variable enzyme Variable and constant enzymes within the alcohol and aldehyde dehydrogenase families FEBS Lett 283 1 ss 85 8 doi 10 1016 0014 5793 91 80559 L PMID 2037078 Santisteban I Povey S West LF ve digerleri 1986 Chromosome assignment biochemical and immunological studies on a human aldehyde dehydrogenase ALDH3 Ann Hum Genet 49 Pt 2 ss 87 100 doi 10 1111 j 1469 1809 1985 tb01680 x PMID 4073832 Teng YS 1981 Stomach aldehyde dehydrogenase report of a new locus Hum Hered 31 2 ss 74 7 doi 10 1159 000153181 PMID 7228061 Dyck LE 1995 Polymorphism of a class 3 aldehyde dehydrogenase present in human saliva and in hair roots Alcohol Clin Exp Res 19 2 ss 420 6 doi 10 1111 j 1530 0277 1995 tb01525 x PMID 7625577 Maruyama K Sugano S 1994 Oligo capping a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides Gene 138 1 2 ss 171 4 doi 10 1016 0378 1119 94 90802 8 PMID 8125298 Hsu LC Yoshida A 1993 Human Stomach Aldehyde Dehydrogenase ALDH3 Enzymology and Molecular Biology of Carbonyl Metabolism 4 Advances in Experimental Medicine and Biology 328 ss 141 52 doi 10 1007 978 1 4615 2904 0 16 ISBN 978 1 4613 6259 3 PMID 8493892 Rogers GR Markova NG De Laurenzi V ve digerleri 1997 Genomic organization and expression of the human fatty aldehyde dehydrogenase gene FALDH Genomics 39 2 ss 127 35 doi 10 1006 geno 1996 4501 PMID 9027499 Tsukamoto N Chang C Yoshida A 1997 Mutations associated with Sjogren Larsson syndrome Ann Hum Genet 61 Pt 3 ss 235 42 doi 10 1046 j 1469 1809 1997 6130235 x PMID 9250352 Suzuki Y Yoshitomo Nakagawa K Maruyama K ve digerleri 1997 Construction and characterization of a full length enriched and a 5 end enriched cDNA library Gene 200 1 2 ss 149 56 doi 10 1016 S0378 1119 97 00411 3 PMID 9373149 Rekha GK Devaraj VR Sreerama L ve digerleri 1998 Inhibition of human class 3 aldehyde dehydrogenase and sensitization of tumor cells that express significant amounts of this enzyme to oxazaphosphorines by chlorpropamide analogues Biochem Pharmacol 55 4 ss 465 74 doi 10 1016 S0006 2952 97 00475 9 PMID 9514081 Simpson JC Wellenreuther R Poustka A ve digerleri 2001 Systematic subcellular localization of novel proteins identified by large scale cDNA sequencing EMBO Rep 1 3 ss 287 92 doi 10 1093 embo reports kvd058 PMC 1083732 2 PMID 11256614 Rodriguez Zavala JS Weiner H 2002 Structural aspects of aldehyde dehydrogenase that influence dimer tetramer formation Biochemistry 41 26 ss 8229 37 doi 10 1021 bi012081x PMID 12081471 Yang M Coles BF Delongchamp R ve digerleri 2003 Effects of the ADH3 CYP2E1 and GSTP1 genetic polymorphisms on their expressions in Caucasian lung tissue Lung Cancer 38 1 ss 15 21 doi 10 1016 S0169 5002 02 00150 2 PMID 12367788